SCHEMBL20137415

SCHEMBL20137415

Clc1nccc2c1sc1cc3ccccc3cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
APEX1 P27695 1/20 0.44
MAPK1 P28482 1/20 0.44
PMP22 Q01453 1/20 0.44
ALDH1A1 P00352 1/20 0.33
CLK1 P49759 1/20 0.30
CCR1 P32246 1/20 0.30
CCR8 P51685 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PI4KA P42356 1/20 0.30
PI4K2B Q8TCG2 1/20 0.30
PI4K2A Q9BTU6 1/20 0.30
PI4KB Q9UBF8 1/20 0.30
DYRK1A Q13627 1/20 0.30
CYP2A6 P11509 1/20 0.30
F12 P00748 1/20 0.30
PLAU P00749 1/20 0.30
NCF1 P14598 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24118989 0.81 CYP2A6 (0.44) MAPTCYP3A4APEX1MAPK1ALDH1A1
SCHEMBL30967228 0.80 GPR3 (0.46) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL442331 0.80 GPR3 (0.46) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL20149676 0.78 PDE3B (0.43) MAPTCYP3A4MAPK1ALDH1A1L3MBTL1
SCHEMBL29823912 0.78
SCHEMBL25547960 0.77 MAPT (0.40) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL25171509 0.77 BCKDK (0.39) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL25175594 0.76 ALDH1A1 (0.41) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL25569972 0.76 CYP3A4 (0.54) MAPTLMNACYP3A4APEX1MAPK1
SCHEMBL24210392 0.75 CYP1A2 (0.45) MAPTLMNAMAPK1ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096465-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-06-01 WO disclosed
EP-4092036-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2022-11-23 EP disclosed
EP-3354654-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-04-27 EP disclosed
US-20210343950-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-11-04 US disclosed
US-20210343950-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-11-04 US disclosed
US-11069864-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-07-20 US disclosed
US-11069864-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-07-20 US disclosed
US-20200251669-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2020-08-06 US disclosed
US-20200251669-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2020-08-06 US disclosed
US-10680188-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-09 US disclosed
US-10680188-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-09 US disclosed
EP-3354654-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-08-01 EP disclosed
US-20180138427-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180138427-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180138427-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10680188-B2 Organic electroluminescent materials and devices AOX1, OCIAD1, OCIAD2 MAPT 2064/4885LMNA 3946/4885CYP3A4 502/4885
US-20200251669-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, OCIAD1, OCIAD2 MAPT 2064/4885LMNA 3946/4885CYP3A4 502/4885
US-20210343950-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, OCIAD1, OCIAD2 MAPT 2064/4885LMNA 3946/4885CYP3A4 502/4885
US-20180138427-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, OCIAD1, OCIAD2 MAPT 2064/4885LMNA 3946/4885CYP3A4 502/4885
US-11069864-B2 Organic electroluminescent materials and devices AOX1, OCIAD1, OCIAD2 MAPT 2064/4885LMNA 3946/4885CYP3A4 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.