Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29139850 | 0.65 | CA2 (0.41) | — | |
| SCHEMBL28170298 | 0.60 | ALDH1A1 (0.41) | — | |
| SCHEMBL22605163 | 0.60 | TDP1 (0.38) | ESR1 | |
| SCHEMBL82932 | 0.60 | — | — | |
| SCHEMBL6363979 | 0.59 | CA2 (0.48) | — | |
| SCHEMBL5078039 | 0.59 | CA2 (0.44) | — | |
| Hypochlorous Acid SCHEMBL11418723 | 0.58 | ALDH1A1 (0.43) | — | |
| SCHEMBL27256806 | 0.58 | CA2 (0.52) | — | |
| SCHEMBL28224078 | 0.58 | L3MBTL1 (0.50) | — | |
| SCHEMBL28160840 | 0.58 | HDAC3 (0.38) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |