Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13419274 | 0.79 | ALDH1A1 (0.47) | ALDH1A1NCF1HTR1AHTR3AMAPT | |
| SCHEMBL15872025 | 0.79 | ALDH1A1 (0.55) | ALDH1A1NCF1HTR1AHTR3AMAPT | |
| SCHEMBL13907868 | 0.77 | MAPT (0.57) | ALDH1A1NCF1HTR1AHTR3AMAPT | |
| SCHEMBL766675 | 0.76 | HTT (0.48) | ALDH1A1MAPTLMNASMN1; SMN2POLB | |
| SCHEMBL27372178 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HTR1AHTR3AMAPTUSP2 | |
| SCHEMBL23981784 | 0.75 | PAX8 (0.41) | ALDH1A1MAPTUSP2THRBLMNA | |
| SCHEMBL614332 | 0.74 | PAX8 (0.43) | ALDH1A1MAPTLMNAKDM4EL3MBTL1 | |
| SCHEMBL27372179 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HTR1AHTR3AMAPTUSP2 | |
| SCHEMBL12005978 | 0.72 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2POLBKDM4E | |
| SCHEMBL24824103 | 0.72 | TSHR (0.54) | ALDH1A1MAPTTHRBSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |