Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129735 | 1.00 | SCN9A (0.35) | SCN9AHSD11B1NOTUMXIAPBIRC2 | |
| SCHEMBL20129736 | 1.00 | SCN9A (0.35) | SCN9AHSD11B1NOTUMXIAPBIRC2 | |
| SCHEMBL20129699 | 0.88 | HTR6 (0.41) | SCN9ASCN5AALDH1A1SMN1; SMN2 | |
| SCHEMBL20141744 | 0.81 | POLB (0.40) | ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL20142150 | 0.81 | TP53 (0.44) | ALDH1A1LMNAPOLBSTS | |
| SCHEMBL20129702 | 0.78 | PKM (0.37) | SCN9ASCN5ANR1H2NR1H3LMNA | |
| SCHEMBL20129727 | 0.76 | ALDH1A1 (0.39) | HSD11B1NOTUMHTR2CALDH1A1SMN1; SMN2 | |
| SCHEMBL22693287 | 0.73 | STS (0.45) | SMN1; SMN2LMNASTS | |
| SCHEMBL20129659 | 0.71 | HTR6 (0.51) | LMNA | |
| SCHEMBL21360394 | 0.71 | HTR6 (0.51) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |