Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 4/20 | 0.42 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.42 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149778 | 0.83 | DRD4 (0.43) | KDM4EALDH1A1DRD4DRD2GRM5 | |
| SCHEMBL13176022 | 0.81 | MEN1 (0.59) | KDM4EALDH1A1DRD4DRD2GRM5 | |
| SCHEMBL31042527 | 0.79 | DRD4 (0.51) | KDM4EALDH1A1DRD4DRD2GRM5 | |
| SCHEMBL18840246 | 0.79 | ROCK2 (0.45) | KDM4EALDH1A1MTORRPTORMLST8 | |
| SCHEMBL3088832 | 0.78 | DRD4 (0.54) | KDM4EALDH1A1DRD4DRD2GRM5 | |
| SCHEMBL2261269 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1DRD4DRD2GRM5 | |
| SCHEMBL8693892 | 0.78 | ADRB1 (0.50) | KDM4EALDH1A1DRD2DRD3CYP2D6 | |
| SCHEMBL20140119 | 0.78 | GRM5 (0.49) | KDM4EALDH1A1DRD4DRD2GRM5 | |
| SCHEMBL7714987 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1DRD4DRD2GRM5 | |
| SCHEMBL20756875 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1DRD4DRD2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |