Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149928 | 0.83 | KDM4E (0.44) | DRD4DRD2DRD3CHRM4KDM1A | |
| SCHEMBL7714987 | 0.83 | KDM4E (0.44) | DRD4DRD2DRD3CHRM4KDM1A | |
| SCHEMBL31042542 | 0.80 | DRD4 (0.45) | DRD4DRD2DRD3CHRM4KDM4E | |
| SCHEMBL7715922 | 0.80 | DRD4 (0.47) | DRD4DRD2DRD3CHRM4KDM4E | |
| SCHEMBL22837836 | 0.79 | HSD17B10 (0.51) | NPY2RKDM4EALDH1A1 | |
| SCHEMBL7955964 | 0.79 | KDM1A (0.43) | DRD4DRD2NPY2RCHRM4KDM1A | |
| SCHEMBL13176022 | 0.78 | MEN1 (0.59) | DRD4DRD2HTR7KDM4EALDH1A1 | |
| SCHEMBL20756875 | 0.77 | KDM4E (0.44) | DRD4DRD2DRD3CHRM4HTR7 | |
| SCHEMBL7711219 | 0.76 | DRD2 (0.48) | DRD4DRD2DRD3CHRM4KDM4E | |
| SCHEMBL31042527 | 0.75 | DRD4 (0.51) | DRD4DRD2DRD3CHRM4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |