Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391401 | 0.79 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1KDM4EL3MBTL1TP53 | |
| SCHEMBL15023628 | 0.76 | TSHR (0.43) | RAPGEF4KAT6AALDH1A1KDM4EL3MBTL1 | |
| Propene SCHEMBL27388590 | 0.76 | MYC (0.46) | RAPGEF4KAT6AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL20156922 | 0.74 | TSHR (0.41) | RAPGEF4KAT6AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL20149699 | 0.74 | TSHR (0.41) | RAPGEF4KAT6AALDH1A1KDM4EL3MBTL1 | |
| Formaldehyde SCHEMBL8587201 | 0.72 | MYC (0.50) | RAPGEF4KAT6AALDH1A1KDM4EL3MBTL1 | |
| Ethylene SCHEMBL8654498 | 0.72 | MYC (0.50) | RAPGEF4KAT6AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10363485 | 0.72 | CA1 (0.43) | RAPGEF4KAT6AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1951142 | 0.72 | TSHR (0.43) | RAPGEF4KAT6AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL305238 | 0.72 | TSHR (0.43) | RAPGEF4KAT6AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |