Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149699 | 1.00 | TSHR (0.41) | TSHRACHERAPGEF4KAT6AALDH1A1 | |
| SCHEMBL15023628 | 0.83 | TSHR (0.43) | TSHRACHERAPGEF4KAT6AALDH1A1 | |
| SCHEMBL12307 | 0.80 | L3MBTL1 (0.50) | TSHRACHERAPGEF4ALDH1A1KDM4E | |
| SCHEMBL28278788 | 0.80 | L3MBTL1 (0.50) | TSHRACHERAPGEF4ALDH1A1KDM4E | |
| SCHEMBL10363485 | 0.79 | CA1 (0.43) | TSHRACHERAPGEF4KAT6AALDH1A1 | |
| SCHEMBL24336054 | 0.79 | KEAP1 (0.36) | TSHRALDH1A1L3MBTL1TP53ESR1 | |
| SCHEMBL305238 | 0.78 | TSHR (0.43) | TSHRACHERAPGEF4KAT6AALDH1A1 | |
| Bromide SCHEMBL28167960 | 0.78 | L3MBTL1 (0.48) | TSHRACHERAPGEF4ALDH1A1KDM4E | |
| SCHEMBL4533183 | 0.77 | TSHR (0.47) | TSHRACHERAPGEF4KAT6AALDH1A1 | |
| SCHEMBL29468592 | 0.77 | ALDH1A1 (0.55) | TSHRACHERAPGEF4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |