SCHEMBL20150324

SCHEMBL20150324

Cc1ccc(-c2ccc3c4ccccc4n(-c4cc(-c5nc(C)nc(C)n5)ccc4C#N)c3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
LMNA P02545 3/20 0.34
HTT P42858 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 5/20 0.33
HPGD P15428 4/20 0.33
ALDH1A1 P00352 4/20 0.33
MAOA P21397 3/20 0.33
GAA P10253 3/20 0.33
MAOB P27338 2/20 0.33
GLA P06280 2/20 0.33
CASP1 P29466 1/20 0.33
RECQL P46063 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PDE9A O76083 1/20 0.33
PDE1C Q14123 1/20 0.33
MAT2A P31153 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20114523 0.95 ALDH1A1 (0.38) L3MBTL1LMNAHTTSMN1; SMN2KDM4E
SCHEMBL20150296 0.94 AR (0.39) ARL3MBTL1SMN1; SMN2KDM4EALDH1A1
SCHEMBL20150330 0.94 MAT2A (0.36) L3MBTL1LMNASMN1; SMN2KDM4EHPGD
SCHEMBL20114509 0.94 KDM4E (0.35) L3MBTL1LMNAHTTSMN1; SMN2TDP1
SCHEMBL20114678 0.93 PTGER4 (0.37) LMNASMN1; SMN2HPGDALDH1A1HSD17B10
SCHEMBL20150310 0.93 GRIN1 (0.33) ARLMNASMN1; SMN2KDM4EHPGD
SCHEMBL20150302 0.92 AR (0.40) ARL3MBTL1LMNASMN1; SMN2KDM4E
SCHEMBL20114668 0.91 ALDH1A1 (0.40) L3MBTL1LMNAHTTSMN1; SMN2TDP1
SCHEMBL20114671 0.90 L3MBTL1 (0.41) L3MBTL1LMNAHTTSMN1; SMN2KDM4E
SCHEMBL20156172 0.90 CYP1A2 (0.34) LMNASMN1; SMN2KDM4EHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421746-B2 Organic molecules, especially for use in organic optoelectronic devices CYNORA GMBH (DE) 2019-09-24 US disclosed
US-20180134686-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-05-17 US disclosed
US-20180134686-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180134686-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, EPCAM, F12 AR 3892/4885L3MBTL1 2736/4885LMNA 3586/4885
US-10421746-B2 Organic molecules, especially for use in organic optoelectronic devices OR10J3, EPCAM, F12 AR 3892/4885L3MBTL1 2736/4885LMNA 3586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.