Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168837 | 0.86 | MAPT (0.49) | TSHRSMN1; SMN2CYP1A2TDP1HPGD | |
| SCHEMBL25470720 | 0.86 | PTGDR2 (0.45) | SMN1; SMN2CYP1A2HPGDHDAC8MAPT | |
| SCHEMBL20137041 | 0.84 | RXRA (0.38) | PPARACYP2C9SMN1; SMN2CYP1A2PPARG | |
| SCHEMBL25470728 | 0.81 | PTGDR2 (0.43) | CYP1A2TDP1HPGDHDAC8ALDH1A1 | |
| SCHEMBL23087387 | 0.81 | PTGDR2 (0.43) | CYP1A2TDP1HPGDHDAC8ALDH1A1 | |
| SCHEMBL23087373 | 0.81 | PTGDR2 (0.43) | CYP1A2TDP1HPGDHDAC8ALDH1A1 | |
| SCHEMBL17821848 | 0.78 | ALDH1A1 (0.43) | TSHRCYP2C9SMN1; SMN2CYP1A2TDP1 | |
| SCHEMBL15082525 | 0.77 | ALDH1A1 (0.52) | TSHRCYP2C9SMN1; SMN2CYP1A2TDP1 | |
| SCHEMBL25778864 | 0.77 | PPARG (0.51) | TSHRPPARACYP2C9SMN1; SMN2TTR | |
| SCHEMBL25470719 | 0.76 | AKR1C3 (0.40) | PPARACYP2C9HDAC8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691975-B2 | MAGL inhibitors | H. LUNDBECKA/S (DK) | 2023-07-04 | — | — | US | disclosed |
| US-20180134674-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | TSHR 4772/4885PPARA 2252/4885CYP2C9 4338/4885 |
| US-11691975-B2 | MAGL inhibitors | MAG, MAGI3, MGLL | TSHR 4825/4885PPARA 1470/4885CYP2C9 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.