Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20151842 | 0.86 | PPARD (0.36) | PPARDKDM4EMAPK1MAPTATM | |
| SCHEMBL20137089 | 0.83 | FFAR4 (0.39) | PPARDKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL29561187 | 0.83 | FFAR4 (0.39) | PPARDKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL20151846 | 0.83 | PPARD (0.38) | PPARDKDM4EMAPK1MAPTATM | |
| Hydrochloric Acid SCHEMBL29560707 | 0.82 | FFAR4 (0.39) | PPARDKDM4EMAPTALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL20137048 | 0.82 | FFAR4 (0.39) | PPARDKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL20151848 | 0.82 | KMT2A (0.36) | PPARDSRCKDM4EMAPK1MAPT | |
| Trifluoroacetic Acid SCHEMBL29561105 | 0.81 | PPARG (0.39) | PPARDKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL20151844 | 0.80 | ALOX5 (0.37) | PPARDKDM4EMAPK1MAPTATM | |
| SCHEMBL20151838 | 0.76 | PPARG (0.39) | KDM4EMAPK1MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | PPARD 2641/4885SRC 3069/4885KDM4E 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.