Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150068 | 0.88 | TSPO (0.39) | ALDH1A1HSD17B10USP2GAABCHE | |
| SCHEMBL20137115 | 0.88 | LTB4R2 (0.44) | PPARGBCHEACHEMAPT | |
| SCHEMBL20151846 | 0.78 | PPARD (0.38) | ALDH1A1HSD17B10MAPK1L3MBTL1LMNA | |
| SCHEMBL20137405 | 0.78 | BCL2A1 (0.38) | ALDH1A1BCHEACHEMEN1KMT2A | |
| SCHEMBL28880216 | 0.78 | BCL2A1 (0.41) | PPARGUSP2L3MBTL1TSHRMEN1 | |
| SCHEMBL20151844 | 0.78 | ALOX5 (0.37) | PPARGALDH1A1HSD17B10MAPK1L3MBTL1 | |
| SCHEMBL20151842 | 0.77 | PPARD (0.36) | ALDH1A1MAPK1L3MBTL1MAPTTSPO | |
| SCHEMBL20137411 | 0.76 | LTB4R2 (0.40) | BCHEMAPT | |
| SCHEMBL20570505 | 0.75 | LTB4R2 (0.42) | PPARGUSP2TSHR | |
| SCHEMBL3459748 | 0.74 | BCHE (0.41) | ALDH1A1MAPK1BCHEACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | PPARG 2047/4885ALDH1A1 4349/4885HSD17B10 4690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.