Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560940 | 0.80 | CYP2D6 (0.52) | MGLLCYP2D6CYP3A4TSHRMEN1 | |
| SCHEMBL20137096 | 0.80 | CYP2D6 (0.52) | MGLLCYP2D6CYP3A4TSHRMEN1 | |
| SCHEMBL20151874 | 0.80 | MGLL (0.75) | MGLLCYP2D6CYP3A4TSHRCYP2C19 | |
| SCHEMBL20151824 | 0.79 | MGLL (1.00) | MGLLCYP2D6 | |
| SCHEMBL20179998 | 0.77 | CYP3A4 (0.56) | CYP2D6CYP3A4TSHRMEN1TP53 | |
| SCHEMBL20151869 | 0.76 | MGLL (0.61) | MGLLCYP2D6CYP3A4TSHRMEN1 | |
| SCHEMBL19262510 | 0.76 | CYP2D6 (0.72) | CYP2D6CYP3A4TSHRMEN1TP53 | |
| SCHEMBL20676125 | 0.75 | CYP2D6 (0.70) | CYP2D6CYP3A4TSHRMEN1TP53 | |
| SCHEMBL28322502 | 0.73 | CYP2D6 (0.48) | MGLLCYP2D6CYP3A4TSHRMEN1 | |
| SCHEMBL28699525 | 0.72 | CYP3A4 (0.47) | MGLLCYP2D6CYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134674-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | MGLL 3/4885CYP2D6 3916/4885CYP3A4 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.