Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407053 | 0.91 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| Hydrogen Peroxide SCHEMBL29156826 | 0.89 | ALDH1A1 (0.56) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| Water SCHEMBL27873279 | 0.89 | ALDH1A1 (0.56) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL30938821 | 0.89 | ALDH1A1 (0.56) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL28515577 | 0.85 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL31633585 | 0.85 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL332803 | 0.85 | NAAA (0.56) | ALDH1A1ATMTSHRHCAR2NAAA | |
| SCHEMBL9480850 | 0.84 | ALDH1A1 (0.40) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL37837 | 0.84 | ALDH1A1 (0.67) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL28118273 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRHPGDHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180133333-A1 | BIODEGRADABLE THERMO-RESPONSIVE POLYMERS AND USES THEREOF | Tht Trustees of Columbia University in the City of New York (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133333-A1 | BIODEGRADABLE THERMO-RESPONSIVE POLYMERS AND USES THEREOF | HEATR6, CHIA, HSF1 | ALDH1A1 205/4885ATM 1899/4885TSHR 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.