Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818778 | 0.89 | ADRA2A (0.38) | DGKAMAPTADRA2AADRA1ADNM1 | |
| SCHEMBL20661419 | 0.89 | HSD17B10 (0.41) | HSD17B10MAPTALDH1A1TSHRBLM | |
| SCHEMBL20661433 | 0.89 | HSD17B10 (0.41) | HSD17B10MAPTALDH1A1TSHRBLM | |
| SCHEMBL19884905 | 0.87 | HSD17B10 (0.43) | DGKAHSD17B10EPHX2ALDH1A1TSHR | |
| SCHEMBL443342 | 0.81 | DGKA (0.50) | DGKAMAPTALDH1A1ADRA2AADRA1A | |
| SCHEMBL17871681 | 0.81 | DGKA (0.56) | DGKAHSD17B10MAPTEPHX2ALDH1A1 | |
| SCHEMBL18751718 | 0.81 | MEN1 (0.40) | HSD17B10ALDH1A1TSHRBLM | |
| SCHEMBL18751715 | 0.81 | MEN1 (0.40) | HSD17B10ALDH1A1TSHRBLM | |
| SCHEMBL18751714 | 0.81 | MEN1 (0.40) | HSD17B10ALDH1A1TSHRBLM | |
| SCHEMBL18751710 | 0.81 | MEN1 (0.40) | HSD17B10ALDH1A1TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180133333-A1 | BIODEGRADABLE THERMO-RESPONSIVE POLYMERS AND USES THEREOF | Tht Trustees of Columbia University in the City of New York (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133333-A1 | BIODEGRADABLE THERMO-RESPONSIVE POLYMERS AND USES THEREOF | HEATR6, CHIA, HSF1 | DGKA 1984/4885HSD17B10 450/4885MAPT 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.