SCHEMBL20152142

SCHEMBL20152142

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5c6c7ccccc7n(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)c6ccc54)cc3)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
ATM Q13315 2/20 0.44
KDM4E B2RXH2 1/20 0.44
KMT2A Q03164 5/20 0.37
MEN1 O00255 4/20 0.37
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
IL1R1 P14778 1/20 0.35
HDAC4 P56524 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18708367 0.99 ATM (0.43) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL18124851 0.99 ATM (0.43) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL26053622 0.99 ATM (0.43) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL26053729 0.99 ATM (0.43) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL20315781 0.99 ATM (0.43) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL23805714 0.99 ATM (0.43) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL25966358 0.97 L3MBTL1 (0.50) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL23805824 0.97 L3MBTL1 (0.49) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL23598390 0.97 L3MBTL1 (0.49) L3MBTL1ATMKDM4EKMT2AMEN1
SCHEMBL25965992 0.96 L3MBTL1 (0.49) L3MBTL1ATMKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662196-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-26 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662196-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, SLCO4C1 L3MBTL1 2317/4885ATM 2986/4885KDM4E 3377/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 L3MBTL1 2317/4885ATM 2986/4885KDM4E 3377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.