SCHEMBL20152171

SCHEMBL20152171

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4c5c6ccccc6n(-c6ncc7c8ccccc8c8ccccc8c7n6)c5ccc43)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
RECQL P46063 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TLR7 Q9NYK1 1/20 0.33
ADORA3 P0DMS8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152211 0.94 ATM (0.36) NPC1LMNAMAPTRECQLRAB9A
SCHEMBL20152173 0.89 GABRP (0.35) NPC1MAPTRAB9AL3MBTL1MEN1
SCHEMBL20152218 0.88 MAPT (0.36) NPC1LMNAMAPTRECQLRAB9A
SCHEMBL20152172 0.88 MAPT (0.35) NPC1LMNAMAPTSMN1; SMN2L3MBTL1
SCHEMBL18124849 0.88 L3MBTL1 (0.38) MAPTTLR7L3MBTL1MEN1KMT2A
SCHEMBL19653845 0.88 L3MBTL1 (0.38) MAPTTLR7L3MBTL1MEN1KMT2A
SCHEMBL19653817 0.86 KDM4E (0.45) L3MBTL1MEN1KMT2AATM
SCHEMBL10027613 0.85 L3MBTL1 (0.41) LMNAMAPTADORA3L3MBTL1MEN1
SCHEMBL21351273 0.84 L3MBTL1 (0.39) NPC1LMNAMAPTRECQLRAB9A
SCHEMBL19653838 0.84 KDM4E (0.33) L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662196-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-26 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662196-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, SLCO4C1 NPC1 214/4885LMNA 2982/4885MAPT 689/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 NPC1 214/4885LMNA 2982/4885MAPT 689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.