SCHEMBL20152218

SCHEMBL20152218

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4c5c6ccccc6n(-c6ccc(-c7ncc8c9ccccc9c9ccccc9c8n7)cc6)c5ccc43)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
NPC1 O15118 2/20 0.36
LMNA P02545 2/20 0.36
RAB9A P51151 2/20 0.36
RECQL P46063 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ATM Q13315 2/20 0.35
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 3/20 0.33
PTK2B Q14289 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXRA P19793 1/20 0.31
MTOR P42345 1/20 0.31
TLR7 Q9NYK1 1/20 0.30
MEN1 O00255 2/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152211 0.92 ATM (0.36) MAPTNPC1LMNARAB9ARECQL
SCHEMBL20152171 0.88 NPC1 (0.34) MAPTNPC1LMNARAB9ARECQL
SCHEMBL20152142 0.88 L3MBTL1 (0.44) MAPTNPC1LMNARAB9AATM
SCHEMBL21351273 0.87 L3MBTL1 (0.39) MAPTNPC1LMNARAB9ARECQL
SCHEMBL23805714 0.87 ATM (0.43) MAPTNPC1LMNARAB9AATM
SCHEMBL18708367 0.87 ATM (0.43) MAPTNPC1LMNARAB9AATM
SCHEMBL18124851 0.87 ATM (0.43) MAPTNPC1LMNARAB9AATM
SCHEMBL20315781 0.87 ATM (0.43) MAPTNPC1LMNARAB9AATM
SCHEMBL26053622 0.87 ATM (0.43) MAPTNPC1LMNARAB9AATM
SCHEMBL26053729 0.87 ATM (0.43) MAPTNPC1LMNARAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662196-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-26 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662196-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, SLCO4C1 MAPT 689/4885NPC1 214/4885LMNA 2982/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 MAPT 689/4885NPC1 214/4885LMNA 2982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.