Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metamelfalan SCHEMBL30781236 | 1.00 | CYP3A4 (0.70) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 | |
| Metamelfalan SCHEMBL6842568 | 1.00 | CYP3A4 (0.70) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 | |
| Metamelfalan SCHEMBL2015272 | 1.00 | CYP3A4 (0.70) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 | |
| Melphalan SCHEMBL4984726 | 0.84 | HIF1A (0.91) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 | |
| SCHEMBL18427979 | 0.84 | IDO1 (0.57) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 | |
| SCHEMBL19714971 | 0.84 | IDO1 (0.57) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 | |
| SCHEMBL18427948 | 0.84 | IDO1 (0.57) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 | |
| SCHEMBL6843476 | 0.83 | SMN1; SMN2 (0.53) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 | |
| SCHEMBL2778981 | 0.83 | NOS3 (0.56) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 | |
| SCHEMBL2778977 | 0.83 | NOS3 (0.56) | CYP3A4ALOX15HIF1APTGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| CN-101066453-A | Solid tumor treating medicine composition | SHANDONG LANJIN BIOENGINEERING (CN) | 2007-11-07 | — | — | CN | claimed |
| CN-101066452-A | Solid tumor treating medicine composition containing | SHANDONG LANJIN BIOENGINEERING (CN) | 2007-11-07 | — | — | CN | claimed |
| CN-101066454-A | Solid tumor treating medicine composition | SHANDONG LANJIN BIOENGINEERING (CN) | 2007-11-07 | — | — | CN | claimed |
| CN-101066451-A | Solid tumor treating medicine composition containing dicloethamine | SHANDONG LANJIN BIOENGINEERING (CN) | 2007-11-07 | — | — | CN | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| CN-1923280-A | Anti-cancer slow release injection containing dichloroethylaminum | KONG QINGZHONG (CN) | 2007-03-07 | — | — | CN | claimed |
| CN-1686550-A | Solid tumor resisting pharmaceutical composition containing dicloethamine | SHANDONG LANJIN BIOLOG ENGINEE (CN) | 2005-10-26 | — | — | CN | claimed |
| CN-1686551-A | Anti-solid tumor pharmaceutical composition | SHANDONG LANJIN BIOLOG ENGINEE (CN) | 2005-10-26 | — | — | CN | claimed |
| CN-1679947-A | Anticarcinogen composition | LANJIN BIOLOG ENGINEERING CO L (CN) | 2005-10-12 | — | — | CN | claimed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-11191719-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2021-12-07 | — | — | US | disclosed |
| US-10463611-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2019-11-05 | — | — | US | disclosed |
| EP-0056565-B1 | DERIVATIVES OF DI(-2-CHLOROETHYL) AMINOPHENYL ALANINE WITH ANTITUMOUR ACTIVITY | PROTER S.p.A. (IT) | 1984-12-05 | — | — | EP | disclosed |
| US-4314999-A | N-Acyl derivatives of glucosamine having antitumor chemotherapeutic acitivity | PROTER S.P.A. (IT) | 1982-02-09 | — | — | US | disclosed |
| US-4216208-A | N-Acyl derivatives of glucosamines having antitumor chemotherapeutic activity | PROTER S.P.A. (IT) | 1980-08-05 | — | — | US | disclosed |