Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20152979 | 0.91 | MAOA (0.35) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL20152912 | 0.69 | HTR1A (0.39) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL20152923 | 0.67 | MAOA (0.45) | MAOAMAOBMEN1KMT2ARPS6KA3 | |
| SCHEMBL20152963 | 0.63 | USP7 (0.34) | MEN1KMT2ACNR1CNR2 | |
| SCHEMBL7106703 | 0.62 | ALDH1A1 (0.42) | MAOAMAOBMEN1KMT2ARPS6KA3 | |
| SCHEMBL29836013 | 0.60 | ESR2 (0.52) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL28597255 | 0.60 | ESR2 (0.42) | MAOAMAOB | |
| SCHEMBL20152962 | 0.60 | TP53 (0.39) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL23908222 | 0.60 | TDP1 (0.47) | MAOBMEN1KMT2A | |
| SCHEMBL19765495 | 0.60 | CA1 (0.41) | MAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |