Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785796 | 0.91 | HPGD (0.39) | HPGDLMNATP53CYP3A4ALOX15 | |
| SCHEMBL20152958 | 0.91 | HPGD (0.39) | HPGDLMNATP53CYP3A4ALOX15 | |
| SCHEMBL20152953 | 0.85 | PDE7A (0.38) | PDE7ACYP3A4ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL20152964 | 0.77 | HDAC1 (0.39) | HPGDLMNATP53CYP3A4ALOX15 | |
| SCHEMBL26890360 | 0.71 | PDE7A (0.34) | PDE7ACYP3A4MAPK1 | |
| SCHEMBL26895373 | 0.69 | SLC6A4 (0.33) | PDE7ATP53CYP3A4MAPK1 | |
| SCHEMBL13999136 | 0.68 | ESR1 (0.40) | TP53ALDH1A1MAOB | |
| SCHEMBL7327510 | 0.68 | ADRA1A (0.49) | HPGDLMNATP53KDM4EALDH1A1 | |
| SCHEMBL29165705 | 0.66 | OPRD1 (0.45) | HPGDLMNATP53CYP3A4ALOX15 | |
| SCHEMBL9418269 | 0.65 | TP53 (0.44) | HPGDLMNATP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |