Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823229 | 0.76 | DRD2 (0.49) | ALDH1A1 | |
| SCHEMBL13999138 | 0.76 | DRD2 (0.49) | ALDH1A1 | |
| SCHEMBL20152958 | 0.73 | HPGD (0.39) | MAPTKDM4ECYP3A4ALDH1A1LMNA | |
| SCHEMBL30785796 | 0.73 | HPGD (0.39) | MAPTKDM4ECYP3A4ALDH1A1LMNA | |
| SCHEMBL20170768 | 0.73 | OPRD1 (0.38) | OPRD1MAPTKDM4ECYP3A4ALDH1A1 | |
| SCHEMBL28486491 | 0.72 | — | — | |
| SCHEMBL21565060 | 0.70 | TP53 (0.41) | OPRD1MAPTKDM4ECYP3A4ALDH1A1 | |
| SCHEMBL12762183 | 0.70 | OPRD1 (0.44) | OPRD1MAPTKDM4ECYP3A4MAPK1 | |
| SCHEMBL69957 | 0.68 | MAPT (0.62) | MAPTKDM4ECYP3A4ALDH1A1LMNA | |
| SCHEMBL13647144 | 0.68 | IDO1 (0.41) | LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947755-B | Synthesis method of biaryl aniline axial chiral derivative | 泽升科技(广州)有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115947755-A | Synthetic method of biarylaniline axial chiral derivative | 泽升科技(广州)有限公司 | 2023-04-11 | — | — | CN | disclosed |