Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20152971 | 0.85 | CA3 (0.39) | HTR2AHTR2CHTR2BPIN1LMNA | |
| SCHEMBL20152962 | 0.85 | TP53 (0.39) | HTR2AHTR2CHTR2BMAOAMAOB | |
| SCHEMBL20153014 | 0.83 | MEN1 (0.38) | HTR2AHTR2CHTR2BMAOAMAOB | |
| SCHEMBL20153027 | 0.81 | MEN1 (0.36) | KDM4E | |
| SCHEMBL27619264 | 0.73 | MEN1 (0.39) | HTR2AHTR2CHTR2BPIN1 | |
| SCHEMBL27051000 | 0.70 | MAOA (0.39) | MAOAMAOBKDM4ELMNA | |
| SCHEMBL10662488 | 0.68 | MAOA (0.37) | MAOAMAOB | |
| SCHEMBL20152954 | 0.68 | HSD17B10 (0.39) | HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL20152960 | 0.68 | ALOX15 (0.39) | HTR2AHTR2CHTR2BLMNA | |
| Hydrochloric Acid SCHEMBL10666195 | 0.67 | MAOA (0.36) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |