Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 4/20 | 0.47 |
| ▸ | BRAF | P15056 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20153234 | 0.79 | KMT2A (0.58) | ADORA2AADORA1ALDH1A1KDM4EKMT2A | |
| SCHEMBL20399779 | 0.78 | RAF1 (0.39) | ADORA2AADORA1RAF1BRAFALDH1A1 | |
| SCHEMBL2205962 | 0.77 | AURKA (0.44) | ADORA2AADORA1KMT2AAURKA | |
| SCHEMBL1029670 | 0.76 | MAPT (0.57) | RAF1BRAFALDH1A1KMT2AMEN1 | |
| SCHEMBL3175111 | 0.76 | CRHBP (0.50) | RAF1BRAFKMT2AMEN1MAPT | |
| SCHEMBL4501339 | 0.75 | AURKA (0.41) | ADORA2AADORA1RAF1BRAFALDH1A1 | |
| SCHEMBL21143710 | 0.74 | L3MBTL1 (0.42) | RAF1BRAFALDH1A1KDM4EKMT2A | |
| SCHEMBL21143838 | 0.74 | CHRM3 (0.38) | RAF1BRAFALDH1A1KDM4EKMT2A | |
| SCHEMBL19708837 | 0.72 | SMN1; SMN2 (0.62) | ADORA2AADORA1ALDH1A1KDM4EKMT2A | |
| SCHEMBL12859521 | 0.72 | NUDT1 (0.59) | ADORA2AADORA1GAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975886-B1 | Potassium channel modulators | CADENT THERAPEUTICS, INC. (US) | 2018-05-22 | — | — | US | disclosed |