Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719037 | 1.00 | HSP90AA1 (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL16719040 | 1.00 | HSP90AA1 (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL20170514 | 0.90 | KCNH2 (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL16719021 | 0.87 | — | — | |
| SCHEMBL16730819 | 0.86 | SLC1A2 (0.35) | HSP90AA1HSP90AB1 | |
| SCHEMBL20169617 | 0.81 | ADRA2C (0.30) | — | |
| SCHEMBL16718973 | 0.81 | ADRA2C (0.30) | — | |
| SCHEMBL16720946 | 0.81 | CYP11B2 (0.32) | — | |
| SCHEMBL16719019 | 0.80 | SCN9A (0.31) | — | |
| SCHEMBL16719058 | 0.78 | SLC1A2 (0.34) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068391-B1 | ARYL LINKED IMIDAZOLE AND TRIAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR IMPROVING THE PHARMACOKINETICS OF A DRUG | MERCK SHARP & DOHME (US) | 2018-05-23 | — | — | EP | claimed |
| US-9975888-B2 | Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug | MERCK SHARP & DOHME CORP. (US) | 2018-05-22 | — | — | US | claimed |
| EP-3068391-B1 | ARYL LINKED IMIDAZOLE AND TRIAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR IMPROVING THE PHARMACOKINETICS OF A DRUG | MERCK SHARP & DOHME (US) | 2018-05-23 | — | — | EP | disclosed |