Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16718973 | 1.00 | ADRA2C (0.30) | ADRA2C | |
| SCHEMBL16719019 | 0.95 | SCN9A (0.31) | — | |
| SCHEMBL16731026 | 0.88 | — | — | |
| SCHEMBL20169608 | 0.88 | — | — | |
| SCHEMBL20170505 | 0.88 | — | — | |
| SCHEMBL20170477 | 0.85 | SCN9A (0.31) | — | |
| SCHEMBL16730970 | 0.82 | TSHR (0.34) | — | |
| SCHEMBL16719028 | 0.81 | SCN9A (0.39) | — | |
| SCHEMBL16720946 | 0.81 | CYP11B2 (0.32) | — | |
| SCHEMBL16718968 | 0.81 | DRD3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975888-B2 | Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug | MERCK SHARP & DOHME CORP. (US) | 2018-05-22 | — | — | US | disclosed |