Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865745 | 1.00 | MMP2 (0.33) | MMP2ADAM17ADAMTS5MEN1ALDH1A1 | |
| SCHEMBL17865757 | 1.00 | MMP2 (0.33) | MMP2ADAM17ADAMTS5MEN1ALDH1A1 | |
| SCHEMBL17865774 | 0.87 | NPC1 (0.39) | MMP2ADAM17ADAMTS5 | |
| SCHEMBL17999632 | 0.87 | PIK3CD (0.35) | MMP2ADAM17ADAMTS5MEN1ALDH1A1 | |
| SCHEMBL17865773 | 0.87 | NPC1 (0.39) | MMP2ADAM17ADAMTS5 | |
| SCHEMBL20952055 | 0.87 | ALDH1A1 (0.35) | MMP2ADAM17ADAMTS5MEN1ALDH1A1 | |
| SCHEMBL19541670 | 0.87 | ALDH1A1 (0.35) | MMP2ADAM17ADAMTS5MEN1ALDH1A1 | |
| SCHEMBL20952034 | 0.86 | ALDH1A1 (0.38) | MMP2ADAM17ADAMTS5MEN1ALDH1A1 | |
| SCHEMBL19541330 | 0.86 | ALDH1A1 (0.38) | MMP2ADAM17ADAMTS5MEN1ALDH1A1 | |
| SCHEMBL17999657 | 0.84 | CHRNB2 (0.33) | MMP2ADAM17ADAMTS5MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975879-B2 | Beta lactams as modulators of glutamate uptake and methods for use thereof | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-22 | — | — | US | claimed |