Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639299 | 0.74 | ALDH1A1 (0.41) | APPMAPTALDH1A1HSD17B10TDP1 | |
| SCHEMBL16455005 | 0.73 | KDM4E (0.34) | APPAKT1MAOAMAPTALDH1A1 | |
| SCHEMBL12920089 | 0.71 | CDC25A (0.34) | APPAKT1 | |
| SCHEMBL29281137 | 0.69 | AKT1 (0.32) | AKT1 | |
| SCHEMBL29281135 | 0.69 | AKT1 (0.32) | AKT1 | |
| SCHEMBL16231160 | 0.63 | MAPT (0.50) | MAOAMAPTALDH1A1THRBALOX15 | |
| SCHEMBL309435 | 0.60 | POLL (0.32) | MAPTALDH1A1ALOX15HIF1ATDP1 | |
| SCHEMBL18403695 | 0.59 | KDM4E (0.36) | MAPTALDH1A1 | |
| SCHEMBL16447238 | 0.58 | APP (0.43) | APPMAPTALDH1A1ALOX15HIF1A | |
| SCHEMBL8745839 | 0.58 | PTGS2 (0.39) | MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089230-A1 | ANTIOXIDANT COMPOUNDS FOR CLEAVE FORMULATIONS THAT SUPPORT LONG READS IN SEQUENCING-BY-SYNTHESIS | QIAGEN SCIENCES LLC (US) | 2018-05-17 | — | — | WO | disclosed |