Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 8/20 | 0.35 |
| ▸ | OXGR1 | Q96P68 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGAV | P06756 | 6/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23677941 | 0.84 | ITGAV (0.54) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL20153460 | 0.79 | SUCNR1 (0.39) | SUCNR1OXGR1ITGB3ITGAVBDKRB1 | |
| SCHEMBL21311521 | 0.77 | ITGB3 (0.38) | SUCNR1OXGR1ITGB3ITGAVBDKRB1 | |
| SCHEMBL21282967 | 0.76 | ITGB3 (0.35) | SUCNR1OXGR1ITGB3ITGAVBDKRB1 | |
| SCHEMBL21311532 | 0.75 | ITGB3 (0.44) | SUCNR1OXGR1ITGB3ITGAVITGB6 | |
| SCHEMBL20140487 | 0.75 | ITGB3 (0.39) | SUCNR1OXGR1ITGB3ITGAVITGB6 | |
| SCHEMBL20153482 | 0.74 | ITGB3 (0.40) | SUCNR1OXGR1ITGB3ITGAVITGB6 | |
| SCHEMBL23559272 | 0.73 | ITGB3 (0.42) | SUCNR1OXGR1ITGB3ITGAVITGB6 | |
| SCHEMBL20158254 | 0.72 | OPRM1 (0.39) | ITGB3ITGAVKCNK3ITGA2B | |
| SCHEMBL20153311 | 0.72 | ITGB3 (0.36) | SUCNR1OXGR1ITGB3ITGAVBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089357-A1 | INDAZOLE DERIVATIVES AS αV INTEGRIN ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |