Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 14/20 | 0.39 |
| ▸ | OXGR1 | Q96P68 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.38 |
| ▸ | ITGAV | P06756 | 6/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521880 | 0.91 | SUCNR1 (0.38) | SUCNR1OXGR1ITGB3ITGAVBDKRB1 | |
| SCHEMBL20153461 | 0.84 | ITGAV (0.59) | ITGB3ITGAVITGB6 | |
| SCHEMBL20153459 | 0.81 | KCNK3 (0.34) | ITGB3ITGAV | |
| SCHEMBL20153712 | 0.79 | SUCNR1 (0.35) | SUCNR1OXGR1ITGB3ITGAVBDKRB1 | |
| SCHEMBL20153379 | 0.79 | ITGB3 (0.33) | SUCNR1OXGR1ITGB3ITGAVITGB6 | |
| SCHEMBL21311521 | 0.77 | ITGB3 (0.38) | SUCNR1OXGR1ITGB3ITGAVBDKRB1 | |
| SCHEMBL20153358 | 0.76 | ITGB3 (0.33) | ITGB3ITGAV | |
| SCHEMBL21311532 | 0.76 | ITGB3 (0.44) | SUCNR1OXGR1ITGB3ITGAVITGB6 | |
| SCHEMBL23559272 | 0.76 | ITGB3 (0.42) | SUCNR1OXGR1ITGB3ITGAVITGB6 | |
| SCHEMBL20140487 | 0.76 | ITGB3 (0.39) | SUCNR1OXGR1ITGB3ITGAVITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2018089353-A1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |