Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23591218 | 0.83 | KMT2A (0.58) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL23937565 | 0.79 | KMT2A (0.60) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL2704297 | 0.78 | TDP1 (0.66) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL20664990 | 0.78 | TDP1 (0.60) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL23591196 | 0.76 | KMT2A (0.50) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21540381 | 0.72 | LMNA (0.47) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL20022964 | 0.72 | SLC6A2 (0.58) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL20022959 | 0.72 | KMT2A (0.53) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL27144 | 0.72 | ALDH1A1 (0.68) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL2706964 | 0.72 | CES2 (0.58) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089648-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2018-05-17 | — | — | WO | disclosed |