SCHEMBL20154397

SCHEMBL20154397

CC(C)(C)c1ccc(N(c2ccc(-c3ccc(-c4ccc(C=C(C#N)C#N)s4)s3)cc2)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
APP P05067 5/20 0.54
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GRIA4 P48058 3/20 0.34
GRIA2 P42262 2/20 0.34
KIF11 P52732 1/20 0.33
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
PRKDC P78527 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23836832 0.98 MAPT (0.52) MAPTAPPMEN1KMT2AALDH1A1
SCHEMBL14762765 0.87 MAPT (0.61) MAPTAPPMEN1KMT2AALDH1A1
SCHEMBL20718538 0.83 MAPT (0.56) MAPTAPPMEN1KMT2AALDH1A1
SCHEMBL11936953 0.83 MAPT (0.74) MAPTAPPMEN1KMT2AALDH1A1
SCHEMBL20718508 0.82 MAPT (0.70) MAPTAPPMEN1KMT2AALDH1A1
SCHEMBL28643094 0.81 MAPT (0.52) MAPTAPPMEN1KMT2AALDH1A1
SCHEMBL23836806 0.80 MAPT (0.39) MAPTAPPALDH1A1KDM4E
SCHEMBL23836819 0.80 MAPT (0.39) MAPTAPPALDH1A1KDM4E
SCHEMBL20717958 0.79 MAPT (0.36) MAPTAPPMEN1KMT2AALDH1A1
SCHEMBL29898512 0.79 MAPT (0.56) MAPTAPPMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11128791-B2 Photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2021-09-21 US disclosed
US-10468614-B2 Photoelectric conversion element, image pick-up element, and image pick-up apparatus CANON KABUSHIKI KAISHA (JP) 2019-11-05 US disclosed
US-20190267545-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND IMAGING ELEMENT AND IMAGING APPARATUS INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2019-08-29 US disclosed
US-20190267411-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICKUP ELEMENT, AND IMAGE PICKUP APPARATUS CANON KABUSHIKI KAISHA (JP) 2019-08-29 US disclosed
US-20180138432-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICK-UP ELEMENT, AND IMAGE PICK-UP APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190267545-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND IMAGING ELEMENT AND IMAGING APPARATUS INCLUDING THE SAME CPNE4, LEF1, EMC1 MAPT 2055/4885APP 1499/4885MEN1 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.