SCHEMBL20718508

SCHEMBL20718508

N#CC(C#N)=Cc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)s1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.70
APP P05067 2/20 0.67
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
ALDH1A1 P00352 3/20 0.36
LMNA P02545 1/20 0.35
SLC16A3 O15427 1/20 0.35
SLC16A1 P53985 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
HPGD P15428 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14762765 0.94 MAPT (0.61) MAPTAPPKMT2AMEN1ALDH1A1
SCHEMBL21784390 0.89 MAPT (0.63) MAPTAPPKMT2AMEN1ALDH1A1
SCHEMBL28648311 0.88 MAPT (0.56) MAPTAPPKMT2AMEN1ALDH1A1
SCHEMBL18318924 0.87 MAPT (0.61) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL16532192 0.87 MAPT (0.51) MAPTAPPKMT2AMEN1ALDH1A1
SCHEMBL29898512 0.85 MAPT (0.56) MAPTAPPKMT2AMEN1ALDH1A1
SCHEMBL29898513 0.85 MAPT (0.56) MAPTAPPKMT2AMEN1ALDH1A1
SCHEMBL31707323 0.85 MAPT (0.53) MAPTAPPKMT2AMEN1ALDH1A1
SCHEMBL18318019 0.84 MAPT (0.95) MAPTAPPKMT2AMEN1ALDH1A1
SCHEMBL22817433 0.84 MAPT (0.64) MAPTAPPKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116577499-B Homogeneous catalysis chemiluminescence kit, and preparation method and application method thereof 同济大学 2023-09-19 CN claimed
CN-116577499-A Homogeneous catalysis chemiluminescence kit, and preparation method and application method thereof 同济大学 2023-08-11 CN claimed
US-11793074-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2023-10-17 US disclosed
CN-116577499-B Homogeneous catalysis chemiluminescence kit, and preparation method and application method thereof 同济大学 2023-09-19 CN disclosed
CN-116577499-A Homogeneous catalysis chemiluminescence kit, and preparation method and application method thereof 同济大学 2023-08-11 CN disclosed
CN-113589593-B Material of alignment layer, preparation method of material and display panel TCL华星光电技术有限公司 2023-05-30 CN disclosed
US-20230145492-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICKUP ELEMENT, AND IMAGE PICKUP APPARATUS CANON KK (JP) 2023-05-11 US disclosed
CN-113589593-A Material of alignment layer, preparation method of material and display panel TCL华星光电技术有限公司 2021-11-02 CN disclosed
US-10978644-B2 Organic compound and organic photoelectric conversion element including the same CANON KABUSHIKI KAISHA (JP) 2021-04-13 US disclosed
EP-3466937-B1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE CANON KK (JP) 2021-03-24 EP disclosed
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 US disclosed
US-10861903-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2020-12-08 US disclosed
US-20200119281-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICKUP ELEMENT, AND IMAGE PICKUP APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-04-16 US disclosed
US-20190267545-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND IMAGING ELEMENT AND IMAGING APPARATUS INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2019-08-29 US disclosed
US-20190148644-A1 ORGANIC COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2019-05-16 US disclosed
US-20190119258-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT CANON KABUSHIKI KAISHA (JP) 2019-04-25 US disclosed
EP-3466937-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE C/o Canon Kabushiki Kaisha (JP) 2019-04-10 EP disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 US disclosed
US-20190088885-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT CANON KABUSHIKI KAISHA (JP) 2019-03-21 US disclosed
US-20190043926-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT CANON KABUSHIKI KAISHA (JP) 2019-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 MAPT 3800/4885APP 1621/4885KMT2A 2556/4885
US-11793074-B2 Organic compound and photoelectric conversion element CRY1, CYP1A1, CCNE2 MAPT 3569/4885APP 903/4885KMT2A 1018/4885
US-10978644-B2 Organic compound and organic photoelectric conversion element including the same ORC3, KCNE1, CRY1 MAPT 4289/4885APP 2728/4885KMT2A 1720/4885
US-10861903-B2 Organic compound and photoelectric conversion element NR2E3, CRY1, CRY2 MAPT 4358/4885APP 1784/4885KMT2A 1711/4885
US-20190267545-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND IMAGING ELEMENT AND IMAGING APPARATUS INCLUDING THE SAME CPNE4, LEF1, EMC1 MAPT 2055/4885APP 1499/4885KMT2A 2494/4885
US-20190119258-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT SCN2B, MRPS22, CTNNA1 MAPT 3956/4885APP 1681/4885KMT2A 1279/4885
US-20190043926-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT NR2E3, CRY1, CRY2 MAPT 4358/4885APP 1784/4885KMT2A 1711/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 MAPT 3800/4885APP 1621/4885KMT2A 2556/4885
US-20190148644-A1 ORGANIC COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT INCLUDING THE SAME ORC3, KCNE1, CRY1 MAPT 4289/4885APP 2728/4885KMT2A 1720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.