Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155692 | 0.87 | SLC6A2 (0.34) | SCN9A | |
| SCHEMBL20155356 | 0.86 | ALDH1A1 (0.34) | — | |
| SCHEMBL20155472 | 0.83 | SCN9A (0.35) | SCN9A | |
| SCHEMBL20155487 | 0.83 | BRD4 (0.33) | SCN9A | |
| SCHEMBL20155007 | 0.81 | SLC6A2 (0.35) | — | |
| SCHEMBL20155291 | 0.79 | BRD4 (0.42) | — | |
| SCHEMBL20155693 | 0.72 | BRD4 (0.36) | SCN9A | |
| SCHEMBL20155038 | 0.72 | BRD4 (0.42) | — | |
| SCHEMBL20155068 | 0.71 | BRD4 (0.41) | — | |
| SCHEMBL20155186 | 0.70 | TDO2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |