Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155075 | 0.83 | NUDT1 (0.42) | ALDH1A1GAAKMT2AMAPTNPSR1 | |
| SCHEMBL20155611 | 0.83 | RAPGEF4 (0.49) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL27870354 | 0.81 | GLA (0.40) | ALDH1A1GAAMAPTHTTCYP2C19 | |
| SCHEMBL20155119 | 0.81 | MAPT (0.41) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL20155425 | 0.79 | SOS1 (0.46) | SOS1MAPK14ALDH1A1GAAL3MBTL1 | |
| SCHEMBL1662774 | 0.79 | MAPK14 (0.41) | SOS1MAPK14ALDH1A1GAAL3MBTL1 | |
| SCHEMBL28924001 | 0.77 | SOS1 (0.63) | SOS1MAPK14ALDH1A1GAAL3MBTL1 | |
| SCHEMBL29454259 | 0.75 | ALDH1A1 (0.42) | SOS1ALDH1A1GAAL3MBTL1MEN1 | |
| SCHEMBL20155539 | 0.75 | GAA (0.40) | SOS1ALDH1A1GAAL3MBTL1MEN1 | |
| SCHEMBL8335509 | 0.74 | MAPT (0.51) | MAPK14ALDH1A1GAAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |