Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139378 | 0.69 | CCR5 (0.36) | — | |
| SCHEMBL20140059 | 0.56 | HTR2A (0.43) | — | |
| SCHEMBL23903006 | 0.56 | HTR1D (0.36) | — | |
| SCHEMBL21286927 | 0.55 | NPC1 (0.38) | PYCR1 | |
| SCHEMBL16682942 | 0.55 | SNCA (0.47) | — | |
| SCHEMBL20139385 | 0.54 | SLC5A1 (0.48) | — | |
| SCHEMBL22213303 | 0.53 | RXRB (0.45) | — | |
| SCHEMBL8130884 | 0.53 | TAAR1 (0.39) | — | |
| SCHEMBL20139705 | 0.53 | ALDH1A1 (0.40) | — | |
| SCHEMBL16682943 | 0.53 | SLC5A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089449-A1 | BENZOCYCLOBUTANE DERIVATIVES USEFUL AS DUAL SGLT1/SGLT2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-17 | — | — | WO | disclosed |