Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919503 | 0.79 | ALDH1A1 (0.36) | GABRA1GABRB2ALDH1A1 | |
| SCHEMBL14200344 | 0.76 | LMNA (0.41) | HTR1DHTR1BLMNARNASEH1CRHR1 | |
| SCHEMBL5165456 | 0.73 | GABRA1 (0.63) | GABRA1GABRB2LMNARNASEH1TRPA1 | |
| SCHEMBL23903284 | 0.73 | ALOX12 (0.37) | GABRA1GABRB2LMNARNASEH1TRPA1 | |
| SCHEMBL765890 | 0.73 | GABRA1 (0.41) | HTR1DGABRA1GABRB2LMNARNASEH1 | |
| SCHEMBL12248233 | 0.72 | LMNA (0.39) | HTR1DHTR1BGABRA1GABRB2LMNA | |
| SCHEMBL13233313 | 0.72 | GABRA1 (0.48) | GABRA1GABRB2LMNAALDH1A1GAA | |
| SCHEMBL14328458 | 0.72 | LMNA (0.48) | LMNARNASEH1CRHR1TRPA1PTGS1 | |
| SCHEMBL15702013 | 0.72 | LMNA (0.35) | HTR1DHTR1BGABRA1GABRB2LMNA | |
| SCHEMBL11810508 | 0.72 | LMNA (0.35) | HTR1DHTR1BGABRA1GABRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203016-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | WO | disclosed |