Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155005 | 0.88 | BRD4 (0.54) | BRD4PLA2G7 | |
| SCHEMBL20155097 | 0.84 | BRD4 (0.37) | BRD4PLA2G7 | |
| SCHEMBL20155007 | 0.62 | SLC6A2 (0.35) | BRD4 | |
| SCHEMBL3380147 | 0.61 | PGR (0.44) | BRPF1 | |
| SCHEMBL1631908 | 0.60 | PGR (0.74) | BRPF1 | |
| SCHEMBL3378360 | 0.59 | PGR (0.43) | PLA2G7 | |
| SCHEMBL15540578 | 0.58 | BRD4 (1.00) | BRD4 | |
| SCHEMBL15069424 | 0.58 | BRD4 (1.00) | BRD4 | |
| SCHEMBL16047428 | 0.57 | BRD4 (0.79) | BRD4 | |
| SCHEMBL24369437 | 0.57 | SLC22A12 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |