Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21562481 | 0.81 | CTSV (0.40) | AKT1CTSVCTSLCTSBCTSS | |
| SCHEMBL20139397 | 0.76 | BCHE (0.44) | LMNAAKT1PTPN1CDC25BBCHE | |
| SCHEMBL3142790 | 0.73 | LMNA (0.63) | LMNAAKT1PTPN1CDC25BBCHE | |
| SCHEMBL7524909 | 0.72 | LMNA (0.48) | LMNAAKT1PTPN1CDC25BBCHE | |
| SCHEMBL7529905 | 0.72 | LMNA (0.48) | LMNAAKT1PTPN1CDC25BBCHE | |
| SCHEMBL9266301 | 0.70 | LMNA (0.52) | LMNAAKT1PTPN1CDC25BBCHE | |
| SCHEMBL21218543 | 0.70 | LMNA (0.52) | LMNAAKT1PTPN1CDC25BBCHE | |
| SCHEMBL24725534 | 0.69 | BCHE (0.50) | LMNAAKT1PTPN1CDC25BBCHE | |
| SCHEMBL21283176 | 0.69 | BCHE (0.50) | LMNAAKT1PTPN1CDC25BBCHE | |
| SCHEMBL21218218 | 0.69 | BCHE (0.50) | LMNAAKT1PTPN1CDC25BBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089449-A1 | BENZOCYCLOBUTANE DERIVATIVES USEFUL AS DUAL SGLT1/SGLT2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-17 | — | — | WO | disclosed |