SCHEMBL7524909

SCHEMBL7524909

O=C1C[C@H](OCc2ccccc2)[C@H](COCc2ccccc2)O1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
AKT1 P31749 1/20 0.47
BCHE P06276 2/20 0.47
ACHE P22303 2/20 0.47
CTSV O60911 1/20 0.44
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CTSS P25774 1/20 0.44
CTSK P43235 1/20 0.44
CTSC P53634 1/20 0.44
CTSF Q9UBX1 1/20 0.44
PDE4D Q08499 1/20 0.43
PSEN1 P49768 2/20 0.43
PSEN2 P49810 2/20 0.43
APH1B Q8WW43 2/20 0.43
NCSTN Q92542 2/20 0.43
APH1A Q96BI3 2/20 0.43
PSENEN Q9NZ42 2/20 0.43
PTPN1 P18031 2/20 0.42
CDC25B P30305 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7529905 1.00 LMNA (0.48) LMNAAKT1BCHEACHECTSV
SCHEMBL21218218 0.91 BCHE (0.50) LMNAAKT1BCHEACHECTSV
SCHEMBL21283176 0.91 BCHE (0.50) LMNAAKT1BCHEACHECTSV
SCHEMBL19223109 0.91 BCHE (0.50) LMNAAKT1BCHEACHECTSV
SCHEMBL9838697 0.91 BCHE (0.50) LMNAAKT1BCHEACHECTSV
SCHEMBL24725534 0.91 BCHE (0.50) LMNAAKT1BCHEACHECTSV
SCHEMBL14429283 0.83 BCHE (0.48) LMNAAKT1BCHEACHECTSV
SCHEMBL20654338 0.81 AKT1 (0.51) LMNAAKT1BCHEACHEPTPN1
SCHEMBL7154872 0.80 LMNA (0.48) LMNAAKT1BCHEACHECTSV
SCHEMBL3142790 0.79 LMNA (0.63) LMNAAKT1BCHEACHEPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448415-B1 Chirality conversion method in lactone sugar compounds HANCHEM CO., LTD. (KR) 2002-09-10 US disclosed
US-20020028955-A1 Chirality conversion method in lactone sugar compounds HANCHEM CO., LTD. (KR) 2002-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028955-A1 Chirality conversion method in lactone sugar compounds TREH, FUT6, TALDO1 LMNA 1562/4885AKT1 608/4885BCHE 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.