Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4B | O94953 | 2/20 | 0.32 |
| ▸ | KDM5C | P41229 | 2/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155529 | 0.77 | CNR2 (0.40) | CNR2KAT2BTOP2AKDM4ETERT | |
| SCHEMBL20155563 | 0.73 | CNR2 (0.42) | CNR2KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL20155109 | 0.72 | ADORA3 (0.56) | DAOKDM4E | |
| SCHEMBL20155615 | 0.69 | GSK3B (0.34) | KDM4E | |
| SCHEMBL20155724 | 0.69 | GSK3B (0.32) | — | |
| SCHEMBL20155157 | 0.69 | GSK3B (0.30) | — | |
| SCHEMBL20155732 | 0.66 | GSK3B (0.30) | — | |
| SCHEMBL20155126 | 0.65 | PDE4D (0.34) | PDE4D | |
| SCHEMBL28549245 | 0.65 | CYP2D6 (0.35) | — | |
| SCHEMBL17870698 | 0.64 | PDE4A (0.40) | DAOPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |