Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933889 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9355749 | 0.78 | TRPA1 (0.42) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL31439401 | 0.78 | TRPA1 (0.52) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL14211932 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Hydrogen Peroxide SCHEMBL8659528 | 0.74 | TRPA1 (0.53) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL11436387 | 0.69 | TRPA1 (0.47) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL17594923 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL9860912 | 0.69 | TSHR (0.38) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL20155769 | 0.68 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL3166363 | 0.68 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134675-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134675-A1 | MAGL INHIBITORS | MAG, MAGI3, MGLL | SMN1; SMN2 1770/4885ALDH1A1 4349/4885CA2 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.