Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGAV | P06756 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912918 | 0.80 | ITGB3 (0.56) | ITGB3ITGAV | |
| SCHEMBL13075500 | 0.75 | ITGAV (0.43) | ITGB3ITGAV | |
| SCHEMBL20156098 | 0.73 | CXCR4 (0.47) | ITGB3ITGAV | |
| SCHEMBL20156071 | 0.71 | MPO (0.35) | ITGAVFGFR4 | |
| SCHEMBL19766449 | 0.70 | GRM1 (0.38) | FGFR4 | |
| SCHEMBL20156331 | 0.67 | MPO (0.37) | ITGAVFGFR4 | |
| SCHEMBL20156351 | 0.67 | MPO (0.35) | ITGAVFGFR4 | |
| SCHEMBL19766448 | 0.65 | GRM1 (0.40) | FGFR4 | |
| SCHEMBL21340243 | 0.65 | BRD4 (0.38) | — | |
| SCHEMBL20156073 | 0.63 | FGFR4 (0.34) | ITGAVFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089358-A1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |