Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.62 |
| ▸ | ITGAV | P06756 | 20/20 | 0.62 |
| ▸ | ITGB6 | P18564 | 14/20 | 0.59 |
| ▸ | ITGB5 | P18084 | 14/20 | 0.59 |
| ▸ | ITGB8 | P26012 | 13/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912864 | 0.94 | ITGB3 (0.60) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL20156301 | 0.91 | ITGB3 (0.57) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL20156349 | 0.84 | ITGB3 (0.49) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL24521899 | 0.83 | ITGB3 (0.67) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL23912890 | 0.83 | ITGB3 (0.58) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL23912902 | 0.82 | ITGB3 (0.53) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL21314345 | 0.80 | ITGB3 (0.69) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL21314347 | 0.80 | ITGB3 (0.69) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL23394787 | 0.80 | ITGB3 (0.69) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL23394773 | 0.80 | ITGB3 (0.69) | ITGB3ITGAVITGB6ITGB5ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089358-A1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |