Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.60 |
| ▸ | ITGAV | P06756 | 20/20 | 0.60 |
| ▸ | ITGB6 | P18564 | 14/20 | 0.57 |
| ▸ | ITGB5 | P18084 | 14/20 | 0.57 |
| ▸ | ITGB8 | P26012 | 13/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156291 | 0.94 | ITGB3 (0.62) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL20156301 | 0.92 | ITGB3 (0.57) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL20156033 | 0.86 | ITGB3 (0.63) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL20156349 | 0.84 | ITGB3 (0.49) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL20156255 | 0.82 | ITGAV (0.66) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL24521899 | 0.81 | ITGB3 (0.67) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL23912890 | 0.81 | ITGB3 (0.58) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL23912902 | 0.81 | ITGB3 (0.53) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL20156282 | 0.80 | ITGB3 (0.57) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL21314347 | 0.78 | ITGB3 (0.69) | ITGB3ITGAVITGB6ITGB5ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |