Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156425 | 0.86 | JAK2 (0.32) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL23367734 | 0.84 | JAK2 (0.31) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL18432591 | 0.75 | PDGFRB (0.43) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL20156420 | 0.69 | JAK2 (0.31) | JAK2JAK1JAK3 | |
| SCHEMBL27470244 | 0.66 | CYP3A4 (0.44) | — | |
| SCHEMBL21451503 | 0.66 | PDGFRB (0.38) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL26052577 | 0.66 | CHRM1 (0.37) | — | |
| SCHEMBL20123151 | 0.65 | ALDH1A1 (0.35) | — | |
| SCHEMBL19113576 | 0.64 | — | — | |
| SCHEMBL12489156 | 0.63 | PDGFRB (0.40) | JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |