Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 11/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 10/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 10/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19102992 | 0.93 | GNAO1 (0.42) | SIGMAR1GNAO1GNAI3GNAI1EPHX1 | |
| SCHEMBL23114622 | 0.93 | GNAO1 (0.42) | SIGMAR1GNAO1GNAI3GNAI1EPHX1 | |
| SCHEMBL13825689 | 0.93 | GNAO1 (0.38) | SIGMAR1GNAO1GNAI3GNAI1EPHX1 | |
| SCHEMBL13285534 | 0.86 | CPN1 (0.38) | SIGMAR1GNAO1GNAI3GNAI1DPP7 | |
| SCHEMBL11280750 | 0.85 | GNAO1 (0.40) | SIGMAR1GNAO1GNAI3GNAI1EPHX1 | |
| SCHEMBL9207753 | 0.83 | SHBG (0.44) | SIGMAR1SHBG | |
| SCHEMBL23065895 | 0.82 | GNAO1 (0.43) | SIGMAR1GNAO1GNAI3GNAI1EPHX1 | |
| SCHEMBL19103004 | 0.82 | GNAI3 (0.34) | SIGMAR1GNAO1GNAI3GNAI1SHBG | |
| SCHEMBL21703732 | 0.82 | GNAO1 (0.42) | GNAO1GNAI3GNAI1EPHX1 | |
| SCHEMBL13259736 | 0.81 | CPN1 (0.33) | GNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |