Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18432688 | 0.78 | GABRP (0.43) | TSHRLMNAGAA | |
| SCHEMBL18432590 | 0.74 | GAA (0.41) | TSHRLMNAGAAMAPTAGTR1 | |
| SCHEMBL20156555 | 0.73 | FLT1 (0.48) | TSHRLMNAMAPT | |
| SCHEMBL13778905 | 0.72 | GRIN2D (0.47) | TSHRCD44GRIN2DGRIN3BGRIN1 | |
| SCHEMBL19931606 | 0.72 | CD44 (0.42) | TSHRCD44GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20156420 | 0.71 | JAK2 (0.31) | — | |
| SCHEMBL574139 | 0.71 | LMNA (0.48) | TSHRCD44GRIN2DGRIN3BGRIN1 | |
| SCHEMBL13180246 | 0.68 | CD44 (0.42) | TSHRCD44GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12811480 | 0.68 | GRIN2D (0.47) | TSHRCD44GRIN2DGRIN3BGRIN1 | |
| SCHEMBL27386561 | 0.67 | LMNA (0.44) | TSHRCD44GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |