Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17522501 | 0.79 | ALDH1A1 (0.44) | ALDH1A1IRAK4TP53CYP3A4 | |
| SCHEMBL20156716 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL13941998 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL25244602 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL12234443 | 0.71 | ALDH1A1 (0.43) | ALDH1A1IRAK4TP53CYP3A4 | |
| SCHEMBL10005671 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL9724896 | 0.71 | ALDH1A1 (0.50) | ALDH1A1IRAK4TP53CYP3A4 | |
| SCHEMBL7153238 | 0.70 | ALDH1A1 (0.44) | ALDH1A1IRAK4TP53CYP3A4 | |
| SCHEMBL22594240 | 0.70 | GRM4 (0.31) | — | |
| SCHEMBL9104370 | 0.70 | ALDH1A1 (0.33) | ALDH1A1IRAK4TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194157-A1 | COALESCING AGENT DERIVED FROM DIOXOLANE DERIVATIVES | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194157-A1 | COALESCING AGENT DERIVED FROM DIOXOLANE DERIVATIVES | ITCH, RNF168, DCTN1 | ALDH1A1 1248/4885IRAK4 3235/4885TP53 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.