Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ARG1 | P05089 | 2/20 | 0.46 |
| ▸ | ARG2 | P78540 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10265570 | 0.90 | PRMT3 (0.51) | CCR3ARG1ARG2 | |
| SCHEMBL895202 | 0.88 | ARG1 (0.63) | CCR3ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894361 | 0.87 | ARG1 (0.62) | CCR3ARG1ARG2 | |
| SCHEMBL10265285 | 0.80 | ARG1 (0.63) | ARG1ARG2 | |
| SCHEMBL10264924 | 0.79 | ARG1 (0.57) | ARG1ARG2 | |
| SCHEMBL20156730 | 0.79 | KCNH2 (0.50) | ARG1ARG2 | |
| SCHEMBL10264827 | 0.79 | ARG1 (0.56) | MEN1KMT2AARG1ARG2 | |
| SCHEMBL895463 | 0.78 | ARG1 (0.62) | CCR3ARG1ARG2 | |
| SCHEMBL894944 | 0.78 | ARG1 (0.67) | ARG1ARG2 | |
| SCHEMBL10265381 | 0.78 | ARG1 (0.53) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089490-A1 | ARGINASE INHIBITOR COMBINATION THERAPIES | CALITHERA BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |